The ionospheric equivalent slab-thickness is an important parameter which measures the skewness of the electron density profile of the ionosphere. In this paper, the diurnal, seasonal, day-to-day and latitudinal variations of ionospheric parameters namely total electron content (TEC), the peak ionization density of F-layer (<I>Nm</I>F2), equivalent slab-thickness (τ) and neutral temperature (<I>T</I><sub>n</sub>) are presented. The simultaneous data of GPS-TEC and <I>Nm</I>F2 from Trivandrum (8.47° N, 76.91° E), Waltair (17.7° N, 83.3° E) and Delhi (28.58° N, 77.21° E) are used to compute the slab-thickness (τ = TEC/<I>Nm</I>F2) of the low sunspot period, 2004–2005. The day-time TEC values at Waltair are found to be greater than those at Trivandrum, while at Delhi the day-time TEC values are much lower compared to those at Trivandrum and Waltair. The trends of variation in the monthly mean diurnal variation of TEC and <I>Nm</I>F2 are similar at Delhi, while they are different at Trivandrum and Waltair during the day-time. The slab-thickness (τ) has shown a pre-sunrise peak around 05:00 LT at all the three stations, except during the summer months over Delhi. A consistent secondary peak in slab-thickness around noon hours has also been observed at Trivandrum and Waltair. During equinox and winter months a large night-time enhancement in the slab-thickness (comparable to the early morning peak in slab-thickness) is observed at Delhi. The latitudinal variation of slab-thickness has shown a decrease from the equatorial station, Trivandrum to the low-mid latitude station, Delhi. The neutral temperatures (<I>T</I><sub>n</sub>) computed from the slab-thickness (τ) has shown a sharp increase around 05:00 LT over Trivandrum and Waltair. Whereas at Delhi, a double peaking around 05:00 and 23:00 LT is observed during winter and equinoctial months. The neutral temperatures computed are compare well with those of the MSIS-90 model derived temperatures.